
产品货号:
Z15598
中文名称:
CYP11B1抗体
英文名称:
Anti-CYP11B1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CYP11B1 Antibody |
指标别名 | cytochrome P450 family 11 subfamily B member 1;CPN1;CYP11B;FHI;P450C11;CYP11B1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | CYP11B1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human CYP11B1(436-450aa RNFYHVPFGFGMRQC). |
实际分子量 | 58KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | CYP11B1(Cytochrome p450,family 11,subfamily B,polypeptide 1),also called Steroid 11-beta-hydroxylase or P450C11,is a steroid hydroxylase found in the zona fasciculata.The CYP11B1 gene functions primarily in mitochondria in the zona fasciculata of the adrenal cortex to convert 11-deoxycortisol to cortisol and 11-deoxycorticosterone to corticosterone.CYP11B1 is a member of the cytochrome P450 superfamily of enzymes.It is mapped on 8q24.3.The CYP11B1 gene contains 9 exons and spans 6.5kb.Using RT-PCR,Kayes-Wandover and White detected CYP11B1 mRNA in human cardiac tissue samples from left and right atria,aorta,apex,intraventricular septum,and atrioventricular node,as well as whole adult and fetal heart.Ventricles did not express CYP11B1.In patients with 11-beta-hydroxylase deficiency leading to hypertension and congenital adrenal hyperplasia,Pascoe et al.identified mutations in the CYP11B1 gene. |
Uniprot ID | P15538 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | cytochrome P450,family 11,subfamily B,polypeptide 1 |
蛋白名全称 | Cytochrome P450 11B1,mitochondrial |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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